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Dentinal hypersensitivity (DH) , is a frequent clinical disorder. It is defined as a pain arising from exposed dentine typically in response to thermal, chemical, tactile or osmotic stimuli. Dentinal hypersensitivity may be caused by several conditions such as a result of periodontal pathologies, trauma, dental bleaching, professional oral hygiene, acid foods and beverages, bad oral hygiene habits or incorrect brushing techniques with consequent gingival recessions, etc. Even the removal of orthodontic fixed appliances could expose teeth to hypersensitivity. Patients are usually treated with topical desensitizing fluorine pastes, sealants and aesthetic filling. Only in last decades these procedures have been supported by a laser-assisted treatment, often combined with classic desensitizing. Application of lasers reveals the effectiveness of this treatment, both immediately and during follow-up after approximately 6 months from the first treatment. As a result, the pain is reduced and in many cases it even disappears. Often the laser therapy is integrated with the use of desensitizing agents that can lead to an improvement in results.